Perfeziona i miei risultati

Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients

Campana, Raffaela ; Moritz, Katharina ; Neubauer, Angela ; Huber, Hans ; Henning, Rainer ; Brodie, Tess M. ; Kaider, Alexandra ; Sallusto, Federica ; Wöhrl, Stefan ; Valenta, Rudolf

In: Scientific reports, 2017, vol. 7, p. 11657

The effects of epicutaneous allergen administration on systemic immune responses in allergic and non-allergic individuals has not been investigated with defined allergen molecules. We studied the effects of epicutaneous administration of rBet v 1 and rBet v 1 fragments on systemic immune responses in allergic and non-allergic subjects. We conducted a clinical trial in which rBet v 1 and two...